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F.A.Q. Section

About Cephadex®

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Description

Cephadex® is manufactured by Cipla and comprises Cephalexin as an active ingredient. Cephalexin is a semisynthetic, beta-lactam antibiotic belonging to the Cephalosporins (1st generation).

Indications:

- upper respiratory tract infections (pharyngitis, otitis media);

- skin and skin structure infections (SSTIs) (streptococcal and staphylococcal skin infections);

- bone infections (osteomyelitis);

- genitourinary infections (cystitis, pyelonephritis, prostatitis).

Cephadex® can prevent endocarditis (inflammation of the heart valve) caused by an infection.

MOA (mechanism of action):

Cephalexin is broad-spectrum antibiotic with bactericidal effect. It hinders the biosynthesis of the cell walls in bacteria leading to their rupture. This eventually leads to bacteria’s death. Cephalexin has shown efficacy against aerobes gram-positive (Staphylococcus aureus (penicillinase-producing strains), Streptococcus pneumoniae (penicillin-susceptible strains), Streptococcus pyogenes); aerobes gram-negative (Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella (Branhamella) catarrhalis, Proteus mirabilis).

Dosage

Cephadex® capsules should be swallowed whole and taken with a full glass of water.

Treatment course is administered for 7 to 14 days.

Continue to take Cephadex® even if you feel well.

Do not stop taking Cephadex® suddenly.

For otitis media (middle ear infection):

Adults: The usual dose is 250 mg taken every 6 hours.

Children (ages 1–14 years): 75–100 mg per kg of body weight, taken daily in divided doses.

The doctor may double the dose in case of severe infection.

For skin and skin structure and bone infections:

Adults: 1–4 g per day taken in divided doses. The usual dose is 250 mg taken every 6 hours or 500 mg taken every 12 hours. If you have a severe infection, your doctor may give you a larger dose.

Children (ages 1–14 years): 25–50 mg per kg of body weight, taken daily in 4 divided doses.

The doctor may double this dose for severe cases.

For genitourinary infections and for pharyngitis:

Adults: the usual dose is 250 mg taken every 6 hours. If you have uncomplicated cystitis, you may be given 500 mg every 12 hours.

Children (ages 1–14 years): 25–50 mg per kg of body weight, taken daily in divided doses.

The doctor may double this dose for severe cases.

For endocarditis prevention:

Adults: 2 g taken 30–60 minutes before your procedure.

Children (ages 1–14 years): 50 mg/kg of body weight taken 30–60 minutes before your procedure.

The total child’s dose shouldn’t exceed the adult dosage.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Cephadex® to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cephadex® are:

  • antibiotic-associated diarrhea
  • dizziness
  • fatigue
  • headache
  • joint pain
  • vaginal itching or discharge

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Cephadex® if you are allergic to Cephalexin or to other Cephalosporins (e.g., Cefaclor, Raniclor, Cefadroxil, Duricef).

Do not take Cephadex® if you are allergic to any ingredient comprised in Cephadex®.

Do not take Cephadex® if you have a history of severe allergic reactions associated with using antibiotics.

Do not take Cephadex® if you have a history of clostridium difficileassociated diarrhea (CDAD).

Do not take Cephadex® if you suffer from an inherited metabolic disorder called porphyria.

Do not take Cephadex® if you experience blood clotting problems and take anticoagulants (e.g., Warfarin), as taking Cephadex® may decrease the ability of blood to clot.

Do not take Cephadex® if you take Metformin (for diabetes type 2 treatment), Probenecid (for gout and hyperuricemia treatment).

Do not take Cephadex® if you experience problems with stomach or bowel (inflammation), kidney or liver, or if you have poor nutrition.

Patients with diabetes mellitus who test their urine for glucose should use glucose tests based on enzymatic glucose oxidase reactions while using Cephadex®.

Do not take Cephadex® if you are pregnant, plan to have a baby or are breastfeeding.

If you are taking vitamin supplements, do not take them for 2 hours before or after taking Cephadex®.

Frequently asked questions

Q: What is Cephadex® used for?

A: Cephadex® is an oral antibiotic effectively used to treat bacterial infections of upper respiratory tract (pharyngitis), bones like osteomyelitis, skin and skin structure, genitourinary tracts (cystitis, prostatitis) etc. Cephadex® is not used to treat viral and yeast infections.

Q: Is Cephadex® safe?

A: Cephadex® is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q: Can I take Cephadex® for a cold?

A: Cephadex® will not work for viral infections like colds, flu and for mycoses.

Q: Does Cephadex® treat sexually transmitted diseases (STDs)?

A: Cephadex® is not approved to treat STDs. It may be used against staph infections, but is not very effective against bacterial vaginosis.

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