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F.A.Q. Section

About Nizral® Cream

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Description

Nizral® Cream is a topical antifungal manufactured by Johnson&Johnson. It is used to treat various skin infections caused by microscopic fungi and yeasts, as well as relieve irritation, itching, swelling, and peeling associated with these infections. Nizral® Cream comprises Ketoconazole as an active ingredient. Ketoconazole is a broad spectrum antifungal agent of azole class.

Indications:

- fungal infections of the skin (also known as dermatophytosis infections) including tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot), and tinea versicolor (dermatomycosis furfuracea, pityriasis versicolor, or tinea flava);

- yeast infections of the skin (Seborrheic Dermatitis, cutaneous candidiasis).

MOA (mechanism of action):

Ketoconazole is an antifungal with strong fungistatic properties. It suppresses infection-causing fungal cells growth by inhibiting the production of ergosterol, triglyceride, and phospholipid, key elements of fungal cell membrane biosynthesis. Lack of the above-mentioned constitutes increases fungal cells permeability and ruins their structure, therefore makes them inable to grow and infect the skin further.

Dosage

Nizral® Cream is normally applied to the skin 1-2 times a day, usually for 1-4 weeks depending on the severity of the skin condition.

How to use Nizral® Cream:

1. Wash your hands before Nizral® Cream application.

2. Make sure the application site is clean and dry prior to applying Nizral® Cream.

3. Apply a small amount of Nizral® Cream to the affected area and gently rub until mostly absorbed.

4. Wash your hands after Nizral® Cream application unless your hands are the treated area.

5. Repeat the application of Nizral® Cream at the same time daily, preferably in the morning and at bedtime.

Do not use bandages or dressings over the Nizral® Cream application site, unless your doctor has told you to.

If you use a topical medication that contains steroid during Nizral® Cream treatment course, you should apply steroid medicine in the morning whilst applying Nizral® Cream in the evening. Do not apply both steroid treatment and Nizral® Cream at once.

Do not shower or bathe right after Nizral® Cream application.

Do not use Nizral® Cream in patients under 18 years old.

Nizral® Cream is for external use only. Do not apply to the mucosal surfaces, eyes, lips, inside of the nose, vagina, penis (urethra) or back passage.

Consult your doctor if your symptoms have not improved within 1 week of Nizral® Cream usage.

Nizral® Cream can be used during pregnancy or breastfeeding. Consult your doctor prior to starting the treatment course.

Consult your doctor on how often to apply Nizral® Cream. Use Nizral® Cream exactly as directed.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.

Overdose

Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

Side effects

The most common side effects associated with the use of Nizral® Cream are:

  • allergic reactions (hives, difficult breathing, swelling of your face, lips, tongue, or throat)
  • burning sensation
  • bleeding
  • discomfort
  • dry skin
  • contact dermatitis
  • tingling
  • rash (also known as nettle rash or urticaria)
  • sticky skin

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not apply Nizral® Cream if you are allergic to Ketoconazole or any other antifungal.

Do not apply Nizral® Cream if you are allergic to any of the other ingredients comprised in Nizral® Cream.

Do not apply Nizral® Cream if you have a history of severe allergic reactions associated with using antifungals.

Do not apply Nizral® Cream if you have liver disease.

If you have HIV-positive status, consult your doctor prior to starting the Nizral® Cream treatment course.

Do not use Nizral® Cream in patients under 18 years old.

Do not use Nizral® Cream for more than 4 weeks without doctor’s approval.

Do not take by mouth. Nizral® Cream is for use only on the skin. Avoid swallowing or getting in your eyes, lips, inside of the nose, vagina, penis, back passage or on any other mucosal surfaces. If it does get there, wash with water.

Do not use bandages or dressings over the Nizral® Cream application site, unless your doctor has told you to.

If you are pregnant or breastfeeding, consult your doctor prior to starting the Nizral® Cream treatment course.

Do not apply more Nizral® Cream than the amount prescribed for you.

Do not use the Nizral® Cream if it has already expired.

Frequently asked questions

Q: Can I use Nizral® Cream during pregnancy?

A: Although Nizral® Cream is considered as safe to use in pregnant patients, you should consult your doctor before starting the treatment course.

Q: Can I use Nizral® Cream to treat acne?

A: No, as Nizral® Cream is ineffective against acne.

Q: Can I use Nizral® Cream intra-vaginally?

A: No. Nizral® Cream is for topical use only, it should not be applied to the mucous surfaces, into the eyes, nose, mouth, back passage, vagina or penis (urethra).

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