Description

Alphagan® Z eye drops are manufactured by Allergan. The active substance comprised in Alphagan® Z is Brimonidine, an alpha adrenergic agonist and ocular hypotensive agent.

Indications:

- high intraocular pressure (IOP) due to open-angle glaucoma (also known as chronic glaucoma);

- high intraocular pressure (IOP) due to other eye conditions (eye trauma, pseudoexfoliation syndrome, pigment dispersion syndrome and corneal arcus).

MOA (mechanism of action):

Brimonidine is a selective alpha2-agonist which acts a strong hypotensive agent without causing mydriasis. It lowers IOP by reducing aqueous humor synthesis and increasing uveoscleral aqueous humor outflow. In a gel formulation, Brimonidine may be effective against erythema due to its vasoconstricting properties.

Dosage

For increased IOP in patients with open-angle glaucoma or ocular hypertension

Adults: instill 1 drop (Brimonidine 0,2%, 0,1%, or 0,15% ophthalmic solution) in the treated eye(s) 3 times daily, at 8-hour interval.

Children over 2 years: instill 1 drop of Brimonidine 0,2% ophthalmic solution in the treated eye(s) 3 times daily, at 8-hour interval.

Brimonidine may be used concomitantly with other ophthalmic medications for lowering IOP. Administer each ophthalmic medication at 10-minute interval.

Precautions

Alphagan® Z eye drops are not intended for use in children under 2 years of age.

Alphagan® Z solution is for topical ophthalmic use only, not for injection.

Alphagan® Z solution is associated with allergic reactions, even following a single dose. Discontinue using Alphagan® Z immediately and contact your physician at the first sign of a rash or allergic reaction.

Avoid contaminating the applicator tip with eye, fingers or another source.

Contact lenses should be removed before administrating Alphagan® Z eye drops and may be reinserted after 15 minutes.

Wash your hands before using the eye drops.

Missing a dose

If you miss a dose you should instill it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 2 to 25 degrees C (36 to 77 degrees F), away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use. Use within one month after opening a container. Keep out of the reach of children.

Side effects

The most common side effects associated with Alphagan® Z eye drops are:

• allergic reactions
• dry mouth
• bad taste in the mouth
• burning, stinging, or itching
• foreign body sensation
• blurred vision
• redness
• mildly swollen or puffy eyes
• sensitivity to light
• upset stomach
• headache
• dizziness

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Alphagan® Z solution is not for injection.

Do not use Alphagan® Z eye drops if you are allergic to Brimonidine.

Do not use Alphagan® Z eye drops if you are allergic to any of the other ingredients comprised in Alphagan® Z eye drops.

Do not use Alphagan® Z eye drops if you have Raynaud's phenomenon, thromboangiitis obliterans (Buerger's disease), depression, scleroderma, Sjogren's syndrome, and orthostatic hypotension.

Alphagan® Z eye drops are not for use in patients with severe, unstable, or uncontrolled cardiac disease, cerebrovascular disease or coronary artery disease.

Discontinue using Alphagan® Z eye drops immediately and contact your physician at the first sign of a rash or allergic reaction.

It is advisable not to use Alphagan® Z eye drops during pregnancy until considered absolutely necessary by your physician.

Frequently asked questions

Q: What is Alphagan® Z solution used for?

A: Alphagan® Z eye drops are a potent antiglaucoma drug used to treat ocular hypertension associated with open-angle glaucoma and other eye disorders.

Q: Are Alphagan® Z eye drops safe?

A: Alphagan® Z eye drops are safe for patients over 2 years of age if used at prescribed doses for the prescribed duration as advised by your doctor.

Q: Are Alphagan® Z eye drops safe in pregnancy?

A: You should not use Alphagan® Z eye drops during pregnancy unless considered absolutely necessary by your physician.

Delivery time is:

Reg.Mail - 14-21 business days, price - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

This is exactly how your parcel will look like (pictures of a real shipping item). It has a look of a regular private letter and does not disclose its contents. Size - 9.4x4.3x0.3 inches (24x11x0.7cm).